The acidic stretch and the C-terminal nuclear export signal motif of NPM1 mutant: are they druggable in AML?
Author:
Funder
Associazione Italiana per la Ricerca sul Cancro
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
https://www.nature.com/articles/s41375-023-02037-1.pdf
Reference26 articles.
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2. Falini B, Brunetti L, Sportoletti P, Martelli MP. NPM1-mutated acute myeloid leukemia: from bench to bedside. Blood. 2020;136:1707–21.
3. Falini B. NPM1-mutated acute myeloid leukemia: new pathogenetic and therapeutic insights and open questions. Am J Hematol. 2023;98:1452–64.
4. Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka HM, et al. International consensus classification of myeloid neoplasms and acute leukemias: integrating morphologic, clinical, and genomic data. Blood. 2022;140:1200–28.
5. Khoury JDSE, Solary E, Abla O, Akkari Y, Alaggio R, Apperley JF, et al. The 5th edition of the world health organization classification of haematolymphoid tumours: myeloid and histiocytic /dendritic neoplasms. Leukemia. 2022;36:1703–19.
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