Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes-Reference-Cited by-同舟云学术

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Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes

Published:2014 Issue: Volume:1 Page:14048
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Spohn Gunther,Schori Christian,Keller Iris,Sladko Katja,Sina Christina,Guler Reto,Schwarz Katrin,Johansen Pål,Jennings Gary T,Bachmann Martin F

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference37 articles.

1. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes;Masters;Nat Immunol,2010

2. Type 2 diabetes as an inflammatory disease;Donath;Nat Rev Immunol,2011

3. Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets;Maedler;J Clin Invest,2002

4. IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat;Ehses;Proc Natl Acad Sci USA,2009

5. Treatment with an interleukin 1 beta antibody improves glycemic control in diet-induced obesity;Osborn;Cytokine,2008

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