A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics
Link
http://www.nature.com/articles/ejhg20168.pdf
Reference26 articles.
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2. Madsen BE, Browning SR : A groupwise association test for rare mutations using a weighted sum statistic. PLoS Genet 2009; 5: e1000384.
3. Wu MC, Lee S, Cai T, Li Y, Boehnke M, Lin X : Rare variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet 2011; 89: 82–93.
4. Lee S, Wu MC, Lin X : Optimal tests for rare variant effects in sequencing association studies. Biostatistics 2012; 13: 762–775.
5. Sun J, Zheng Y, Hsu L : A unified mixed-effects model for rare-variant association in sequencing studies. Genet Epidemiol 2013; 37: 334–344.
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