Redundant enhancers and causal variants in the TCF7L2 gene
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics
Link
http://www.nature.com/articles/ejhg201417.pdf
Reference32 articles.
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2. Saxena R, Elbers CC, Guo Y et al: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet 2012; 90: 410–425.
3. Gaulton KJ, Nammo T, Pasquali L et al: A map of open chromatin in human pancreatic islets. Nat Genet 2010; 42: 255–259.
4. Stitzel ML, Sethupathy P, Pearson DS et al: Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci. Cell Metab 2010; 12: 443–455.
5. Lyssenko V, Lupi R, Marchetti P et al: Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest 2007; 117: 2155–2163.
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4. Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes;Genome Research;2016-11-28
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