4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep29489.pdf
Reference38 articles.
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2. Zhuchenko, O. et al. Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel. Nat Genet 15, 62–69, doi: 10.1038/ng0197-62 (1997).
3. Hillman, D. et al. Localization of P-type calcium channels in the central nervous system. Proc Natl Acad Sci USA 88, 7076–7080 (1991).
4. Westenbroek, R. E. et al. Immunochemical identification and subcellular distribution of the alpha 1A subunits of brain calcium channels. J Neurosci 15, 6403–6418 (1995).
5. Yang, Q. et al. Morphological Purkinje cell changes in spinocerebellar ataxia type 6. Acta neuropathologica 100, 371–376 (2000).
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