Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
Author:
Publisher
Springer Science and Business Media LLC
Subject
Computer Science Applications,Biomedical Engineering,Medicine (miscellaneous),Bioengineering,Biotechnology
Link
http://www.nature.com/articles/s41551-019-0498-9.pdf
Reference68 articles.
1. Shanks, N., Greek, R. & Greek, J. Are animal models predictive for humans? Philos. Ethics Humanit. Med. 4, 2 (2009).
2. Malinowski, H. et al. Draft guidance for industry extended-release solid oral dosage forms. Development, evaluation and application of in vitro-in vivo correlations. Adv. Exp. Med. Biol. 423, 269–288 (1997).
3. Danhof, M., de Lange, E. C. M., Della Pasqua, O. E., Ploeger, B. A. & Voskuyl, R. A. Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research. Trends Pharmacol. Sci. 29, 186–191 (2008).
4. Abaci, H. E. & Shuler, M. L. Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling. Integr. Biol. 7, 383–391 (2015).
5. Esch, M. B., Ueno, H., Applegate, D. R. & Shuler, M. L. Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue. Lab Chip 16, 2719–2729 (2016).
Cited by 274 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Recent Advances in Gut‐ and Gut–Organ‐Axis‐on‐a‐Chip Models;Advanced Healthcare Materials;2024-02-03
2. A Scoping Review on the Advent of Microfluidic Devices in Dentistry;Current Oral Health Reports;2024-02-02
3. Developing an adult stem cell derived microphysiological intestinal system for predicting oral prodrug bioconversion and permeability in humans;Lab on a Chip;2024
4. Evaluation of a microphysiological human placental barrier model for studying placental drug transfer;Reproductive Toxicology;2024-01
5. Major on-chip applications;Human Organs-On-a-chip;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3