An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene-Reference-Cited by-同舟云学术

An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

Published:2016-01 Issue:1 Volume:5 Page:1-12
ISSN:2222-1751
Container-title:Emerging Microbes & Infections
language:en
Short-container-title:Emerging Microbes & Infections

Author:

Sun Zhiwu¹,Zhu Yun²,Wang Qian¹,Ye Ling³,Dai Yanyan¹,Su Shan¹,Yu Fei¹,Ying Tianlei¹,Yang Chinglai³,Jiang Shibo¹⁴,Lu Lu¹

Affiliation:

1. Key Laboratory of Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, China

2. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

3. Department of Microbiology and Immunology and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA

4. Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Link

http://www.nature.com/articles/emi201686.pdf

Reference48 articles.

1. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

2. HIV Vaccine Development — Improving on Natural Immunity

3. The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

4. GP120: Target for Neutralizing HIV-1 Antibodies

5. The Rational Design of an AIDS Vaccine

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