Selective ablation of the YxxM motif of IL-7Rα suppresses lymphomagenesis but maintains lymphocyte development
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2010133.pdf
Reference40 articles.
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3. Adams JM, Harris AW, Strasser A, Ogilvy S, Cory S . (1999). Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector. Oncogene 18: 5268–5277.
4. Barata JT, Cardoso AA, Nadler LM, Boussiotis VA . (2001). Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1). Blood 98: 1524–1531.
5. Barata JT, Silva A, Brandao JG, Nadler LM, Cardoso AA, Boussiotis VA . (2004). Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells. J Exp Med 200: 659–669.
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