Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
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Published:2015-11-09
Issue:12
Volume:47
Page:1415-1425
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Gaulton Kyle JORCID, , Ferreira Teresa, Lee Yeji, Raimondo Anne, Mägi Reedik, Reschen Michael E, Mahajan Anubha, Locke Adam, William Rayner N, Robertson Neil, Scott Robert A, Prokopenko Inga, Scott Laura J, Green Todd, Sparso Thomas, Thuillier Dorothee, Yengo Loic, Grallert Harald, Wahl Simone, Frånberg Mattias, Strawbridge Rona J, Kestler Hans, Chheda Himanshu, Eisele Lewin, Gustafsson Stefan, Steinthorsdottir Valgerdur, Thorleifsson Gudmar, Qi Lu, Karssen Lennart C, van Leeuwen Elisabeth M, Willems Sara M, Li Man, Chen Han, Fuchsberger Christian, Kwan Phoenix, Ma Clement, Linderman Michael, Lu Yingchang, Thomsen Soren K, Rundle Jana K, Beer Nicola L, van de Bunt Martijn, Chalisey Anil, Kang Hyun Min, Voight Benjamin F, Abecasis Gonçalo R, Almgren Peter, Baldassarre Damiano, Balkau Beverley, Benediktsson Rafn, Blüher Matthias, Boeing Heiner, Bonnycastle Lori L, Bottinger Erwin P, Burtt Noël P, Carey Jason, Charpentier Guillaume, Chines Peter S, Cornelis Marilyn C, Couper David J, Crenshaw Andrew T, van Dam Rob M, Doney Alex S F, Dorkhan Mozhgan, Edkins Sarah, Eriksson Johan G, Esko Tonu, Eury Elodie, Fadista João, Flannick Jason, Fontanillas Pierre, Fox Caroline, Franks Paul W, Gertow Karl, Gieger Christian, Gigante Bruna, Gottesman Omri, Grant George B, Grarup Niels, Groves Christopher J, Hassinen Maija, Have Christian T, Herder Christian, Holmen Oddgeir L, Hreidarsson Astradur B, Humphries Steve E, Hunter David J, Jackson Anne U, Jonsson Anna, Jørgensen Marit E, Jørgensen Torben, Kao Wen-Hong L, Kerrison Nicola D, Kinnunen Leena, Klopp Norman, Kong Augustine, Kovacs Peter, Kraft Peter, Kravic Jasmina, Langford Cordelia, Leander Karin, Liang Liming, Lichtner Peter, Lindgren Cecilia M, Lindholm Eero, Linneberg Allan, Liu Ching-Ti, Lobbens Stéphane, Luan Jian'an, Lyssenko Valeriya, Männistö Satu, McLeod Olga, Meyer Julia, Mihailov Evelin, Mirza Ghazala, Mühleisen Thomas W, Müller-Nurasyid Martina, Navarro Carmen, Nöthen Markus M, Oskolkov Nikolay N, Owen Katharine R, Palli Domenico, Pechlivanis Sonali, Peltonen Leena, Perry John R B, Platou Carl G P, Roden Michael, Ruderfer Douglas, Rybin Denis, van der Schouw Yvonne T, Sennblad Bengt, Sigurðsson Gunnar, Stančáková Alena, Steinbach Gerald, Storm Petter, Strauch Konstantin, Stringham Heather M, Sun Qi, Thorand Barbara, Tikkanen Emmi, Tonjes Anke, Trakalo Joseph, Tremoli Elena, Tuomi Tiinamaija, Wennauer Roman, Wiltshire Steven, Wood Andrew R, Zeggini Eleftheria, Dunham Ian, Birney Ewan, Pasquali Lorenzo, Ferrer Jorge, Loos Ruth J F, Dupuis Josée, Florez Jose C, Boerwinkle Eric, Pankow James S, van Duijn Cornelia, Sijbrands Eric, Meigs James B, Hu Frank B, Thorsteinsdottir Unnur, Stefansson Kari, Lakka Timo A, Rauramaa Rainer, Stumvoll Michael, Pedersen Nancy L, Lind Lars, Keinanen-Kiukaanniemi Sirkka M, Korpi-Hyövälti Eeva, Saaristo Timo E, Saltevo Juha, Kuusisto Johanna, Laakso Markku, Metspalu Andres, Erbel Raimund, Jöcke Karl-Heinz, Moebus Susanne, Ripatti Samuli, Salomaa Veikko, Ingelsson Erik, Boehm Bernhard O, Bergman Richard N, Collins Francis S, Mohlke Karen L, Koistinen Heikki, Tuomilehto Jaakko, Hveem Kristian, Njølstad Inger, Deloukas Panagiotis, Donnelly Peter J, Frayling Timothy M, Hattersley Andrew T, de Faire Ulf, Hamsten Anders, Illig Thomas, Peters Annette, Cauchi Stephane, Sladek Rob, Froguel Philippe, Hansen Torben, Pedersen Oluf, Morris Andrew D, Palmer Collin N A, Kathiresan Sekar, Melander Olle, Nilsson Peter M, Groop Leif C, Barroso Inês, Langenberg Claudia, Wareham Nicholas J, O'Callaghan Christopher A, Gloyn Anna L, Altshuler DavidORCID, Boehnke Michael, Teslovich Tanya M, McCarthy Mark I, Morris Andrew P
Publisher
Springer Science and Business Media LLC
Reference75 articles.
1. Kooner, J.S. et al. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat. Genet. 43, 984–989 (2011). 2. Cho, Y.S. et al. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians. Nat. Genet. 44, 67–72 (2012). 3. Voight, B.F. et al. Twelve type 2 diabetes susceptibility loci identified through large scale association analysis. Nat. Genet. 42, 579–589 (2010). 4. Morris, A.P. et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 44, 981–990 (2012). 5. Mahajan, A. et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat. Genet. 46, 234–244 (2014).
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