Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
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Published:2014-02-09
Issue:3
Volume:46
Page:234-244
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Mahajan Anubha, , Go Min Jin, Zhang Weihua, Below Jennifer E, Gaulton Kyle J, Ferreira Teresa, Horikoshi Momoko, Johnson Andrew D, Ng Maggie C Y, Prokopenko Inga, Saleheen Danish, Wang Xu, Zeggini Eleftheria, Abecasis Goncalo R, Adair Linda S, Almgren Peter, Atalay Mustafa, Aung Tin, Baldassarre Damiano, Balkau Beverley, Bao Yuqian, Barnett Anthony H, Barroso Ines, Basit Abdul, Been Latonya F, Beilby John, Bell Graeme I, Benediktsson Rafn, Bergman Richard N, Boehm Bernhard O, Boerwinkle Eric, Bonnycastle Lori L, Burtt Noël, Cai Qiuyin, Campbell Harry, Carey Jason, Cauchi Stephane, Caulfield Mark, Chan Juliana C N, Chang Li-Ching, Chang Tien-Jyun, Chang Yi-Cheng, Charpentier Guillaume, Chen Chien-Hsiun, Chen Han, Chen Yuan-Tsong, Chia Kee-Seng, Chidambaram Manickam, Chines Peter S, Cho Nam H, Cho Young Min, Chuang Lee-Ming, Collins Francis S, Cornelis Marilyn C, Couper David J, Crenshaw Andrew T, van Dam Rob M, Danesh John, Das Debashish, de Faire Ulf, Dedoussis George, Deloukas Panos, Dimas Antigone S, Dina Christian, Doney Alex S F, Donnelly Peter J, Dorkhan Mozhgan, van Duijn Cornelia, Dupuis Josée, Edkins Sarah, Elliott Paul, Emilsson Valur, Erbel Raimund, Eriksson Johan G, Escobedo Jorge, Esko Tonu, Eury Elodie, Florez Jose C, Fontanillas Pierre, Forouhi Nita G, Forsen Tom, Fox Caroline, Fraser Ross M, Frayling Timothy M, Froguel Philippe, Frossard Philippe, Gao Yutang, Gertow Karl, Gieger Christian, Gigante Bruna, Grallert Harald, Grant George B, Groop Leif C, Groves Christopher J, Grundberg Elin, Guiducci Candace, Hamsten Anders, Han Bok-Ghee, Hara Kazuo, Hassanali Neelam, Hattersley Andrew T, Hayward Caroline, Hedman Asa K, Herder Christian, Hofman Albert, Holmen Oddgeir L, Hovingh Kees, Hreidarsson Astradur B, Hu Cheng, Hu Frank B, Hui Jennie, Humphries Steve E, Hunt Sarah E, Hunter David J, Hveem Kristian, Hydrie Zafar I, Ikegami Hiroshi, Illig Thomas, Ingelsson Erik, Islam Muhammed, Isomaa Bo, Jackson Anne U, Jafar Tazeen, James Alan, Jia Weiping, Jöckel Karl-Heinz, Jonsson Anna, Jowett Jeremy B M, Kadowaki Takashi, Kang Hyun Min, Kanoni Stavroula, Kao Wen Hong L, Kathiresan Sekar, Kato Norihiro, Katulanda Prasad, Keinanen-Kiukaanniemi Sirkka M, Kelly Ann M, Khan Hassan, Khaw Kay-Tee, Khor Chiea-Chuen, Kim Hyung-Lae, Kim Sangsoo, Kim Young Jin, Kinnunen Leena, Klopp Norman, Kong Augustine, Korpi-Hyövälti Eeva, Kowlessur Sudhir, Kraft Peter, Kravic Jasmina, Kristensen Malene M, Krithika S, Kumar Ashish, Kumate Jesus, Kuusisto Johanna, Kwak Soo Heon, Laakso Markku, Lagou Vasiliki, Lakka Timo A, Langenberg Claudia, Langford Cordelia, Lawrence Robert, Leander Karin, Lee Jen-Mai, Lee Nanette R, Li Man, Li Xinzhong, Li Yun, Liang Junbin, Liju Samuel, Lim Wei-Yen, Lind Lars, Lindgren Cecilia M, Lindholm Eero, Liu Ching-Ti, Liu Jian Jun, Lobbens Stéphane, Long Jirong, Loos Ruth J F, Lu Wei, Luan Jian'an, Lyssenko Valeriya, Ma Ronald C W, Maeda Shiro, Mägi Reedik, Männistö Satu, Matthews David R, Meigs James B, Melander Olle, Metspalu Andres, Meyer Julia, Mirza Ghazala, Mihailov Evelin, Moebus Susanne, Mohan Viswanathan, Mohlke Karen L, Morris Andrew D, Mühleisen Thomas W, Müller-Nurasyid Martina, Musk Bill, Nakamura Jiro, Nakashima Eitaro, Navarro Pau, Ng Peng-Keat, Nica Alexandra C, Nilsson Peter M, Njølstad Inger, Nöthen Markus M, Ohnaka Keizo, Ong Twee Hee, Owen Katharine R, Palmer Colin N A, Pankow James S, Park Kyong Soo, Parkin Melissa, Pechlivanis Sonali, Pedersen Nancy L, Peltonen Leena, Perry John R B, Peters Annette, Pinidiyapathirage Janani M, Platou Carl G P, Potter Simon, Price Jackie F, Qi Lu, Radha Venkatesan, Rallidis Loukianos, Rasheed Asif, Rathmann Wolfgang, Rauramaa Rainer, Raychaudhuri Soumya, Rayner N William, Rees Simon D, Rehnberg Emil, Ripatti Samuli, Robertson Neil, Roden Michael, Rossin Elizabeth J, Rudan Igor, Rybin Denis, Saaristo Timo E, Salomaa Veikko, Saltevo Juha, Samuel Maria, Sanghera Dharambir K, Saramies Jouko, Scott James, Scott Laura J, Scott Robert A, Segrè Ayellet V, Sehmi Joban, Sennblad Bengt, Shah Nabi, Shah Sonia, Shera A Samad, Shu Xiao Ou, Shuldiner Alan R, Sigurðsson Gunnar, Sijbrands Eric, Silveira Angela, Sim Xueling, Sivapalaratnam Suthesh, Small Kerrin S, So Wing Yee, Stančáková Alena, Stefansson Kari, Steinbach Gerald, Steinthorsdottir Valgerdur, Stirrups Kathleen, Strawbridge Rona J, Stringham Heather M, Sun Qi, Suo Chen, Syvänen Ann-Christine, Takayanagi Ryoichi, Takeuchi Fumihiko, Tay Wan Ting, Teslovich Tanya M, Thorand Barbara, Thorleifsson Gudmar, Thorsteinsdottir Unnur, Tikkanen Emmi, Trakalo Joseph, Tremoli Elena, Trip Mieke D, Tsai Fuu Jen, Tuomi Tiinamaija, Tuomilehto Jaakko, Uitterlinden Andre G, Valladares-Salgado Adan, Vedantam Sailaja, Veglia Fabrizio, Voight Benjamin F, Wang Congrong, Wareham Nicholas J, Wennauer Roman, Wickremasinghe Ananda R, Wilsgaard Tom, Wilson James F, Wiltshire Steven, Winckler Wendy, Wong Tien Yin, Wood Andrew R, Wu Jer-Yuarn, Wu Ying, Yamamoto Ken, Yamauchi Toshimasa, Yang Mingyu, Yengo Loic, Yokota Mitsuhiro, Young Robin, Zabaneh Delilah, Zhang Fan, Zhang Rong, Zheng Wei, Zimmet Paul Z, Altshuler David, Bowden Donald W, Cho Yoon Shin, Cox Nancy J, Cruz Miguel, Hanis Craig L, Kooner Jaspal, Lee Jong-YoungORCID, Seielstad Mark, Teo Yik Ying, Boehnke Michael, Parra Esteban J, Chambers John C, Tai E Shyong, McCarthy Mark I, Morris Andrew P, , , ,
Publisher
Springer Science and Business Media LLC
Reference51 articles.
1. Zeggini, E. et al. Meta-analysis of genome-wide association data and large-scale replication identified additional susceptibility loci for type 2 diabetes. Nat. Genet. 40, 638–645 (2008). 2. Kong, A. et al. Parental origin of sequence variants associated with complex diseases. Nature 462, 868–874 (2009). 3. Dupuis, J. et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat. Genet. 42, 105–116 (2010). 4. Voight, B.F. et al. Twelve type 2 diabetes susceptibility loci identified through large scale association analysis. Nat. Genet. 42, 579–589 (2010). 5. Morris, A.P. et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 44, 981–990 (2012).
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