Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome-Reference-Cited by-同舟云学术

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Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

Published:2009-04-12 Issue:5 Volume:16 Page:528-533
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Voorhees Rebecca M,Weixlbaumer Albert,Loakes David,Kelley Ann C,Ramakrishnan V

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb.1577.pdf

Reference44 articles.

1. Nissen, P., Hansen, J., Ban, N., Moore, P.B. & Steitz, T.A. The structural basis of ribosome activity in peptide bond synthesis. Science 289, 920–930 (2000).

2. Steitz, T.A. Structural insights into the functions of the large ribosomal subunit, a major antibiotic target. Keio J. Med. 57, 1–14 (2008).

3. Rodnina, M.V., Beringer, M. & Wintermeyer, W. Mechanism of peptide bond formation on the ribosome. Q. Rev. Biophys. 39, 203–225 (2006).

4. Korostelev, A., Trakhanov, S., Laurberg, M. & Noller, H.F. Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements. Cell 126, 1065–1077 (2006).

5. Bashan, A. et al. Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression. Mol. Cell 11, 91–102 (2003).

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