A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation-Reference-Cited by-同舟云学术

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A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation

Published:2012-01-22 Issue:3 Volume:13 Page:300-307
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Ochiai Kyoko,Maienschein-Cline Mark,Mandal Malay,Triggs Joseph R,Bertolino Eric,Sciammas Roger,Dinner Aaron R,Clark Marcus R,Singh Harinder

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.2210.pdf

Reference38 articles.

1. Herzog, S., Reth, M. & Jumaa, H. Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nat. Rev. Immunol. 9, 195–205 (2009).

2. Geier, J.K. & Schlissel, M.S. Pre-BCR signals and the control of Ig gene rearrangements. Semin. Immunol. 18, 31–39 (2006).

3. Johnson, K. et al. Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity 28, 335–345 (2008).

4. Lu, R., Medina, K.L., Lancki, D.W. & Singh, H. IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 17, 1703–1708 (2003).

5. Mandal, M. et al. Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nat. Immunol. 10, 1110–1117 (2009).

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