Cytotoxic xanthone–anthraquinone heterodimers from an unidentified fungus of the order Hypocreales (MSX 17022)

Author:

Ayers Sloan,Graf Tyler N,Adcock Audrey F,Kroll David J,Shen Qi,Swanson Steven M,Matthew Susan,Carcache de Blanco Esperanza J,Wani Mansukh C,Darveaux Blaise A,Pearce Cedric J,Oberlies Nicholas H

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Reference21 articles.

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2. Pearce, C., Eckard, P., Gruen-Wollny, I. & Hanske, F. G. Microorganisms: their role in the discovery and development of medicines. in Natural Product Chemistry for Drug Discovery (eds A. D. Buss & M. S. Butler) 215–244 The Royal Society of Chemistry, Cambridge, UK, 2010.

3. Fujita, T. et al. Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. J. Antibiot. 47, 208–215 (1994).

4. Fujita, T. et al. Fungal metabolites. Part 12. Potent immunosuppressant, 14-deoxomyriocin, (2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2-hydroxymethyleicos-6-enoic acid and structure-activity relationships of myriocin derivatives. J. Antibiot. 47, 216–224 (1994).

5. Strader, C. R., Pearce, C. J. & Oberlies, N. H. Fingolimod (FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metabolite. J. Nat. Prod. 74, 900–907 (2011).

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