Decade-long leukaemia remissions with persistence of CD4+ CAR T cells-Reference-Cited by-同舟云学术

Decade-long leukaemia remissions with persistence of CD4+ CAR T cells

Published:2022-02-02 Issue:7897 Volume:602 Page:503-509
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Melenhorst J. Joseph^ORCID,Chen Gregory M.,Wang Meng^ORCID,Porter David L.,Chen Changya,Collins McKensie A.,Gao Peng,Bandyopadhyay Shovik,Sun Hongxing,Zhao Ziran,Lundh Stefan,Pruteanu-Malinici Iulian,Nobles Christopher L.,Maji Sayantan,Frey Noelle V.,Gill Saar I.,Loren Alison W.,Tian Lifeng^ORCID,Kulikovskaya Irina,Gupta Minnal,Ambrose David E.,Davis Megan M.,Fraietta Joseph A.,Brogdon Jennifer L.,Young Regina M.,Chew Anne,Levine Bruce L.^ORCID,Siegel Donald L.^ORCID,Alanio Cécile^ORCID,Wherry E. John^ORCID,Bushman Frederic D.^ORCID,Lacey Simon F.,Tan Kai,June Carl H.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-021-04390-6.pdf

Reference27 articles.

1. Kalos, M. et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci. Transl. Med. 3, 95ra73 (2011).

2. Fraietta, J. A. et al. Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia. Nat. Med. 24, 563–571 (2018).

3. Porter, D. L. et al. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia. Sci. Transl. Med. 7, 303ra139 (2015).

4. Frey, N. V. et al. Long-term outcomes from a randomized dose optimization study of chimeric antigen receptor modified T cells in relapsed chronic lymphocytic leukemia. J. Clin. Oncol. Jco1903237 (2020).

5. Brentjens, R. J. et al. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 118, 4817–4828 (2011).

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