Evaluating Systems Pharmacology Models Is Different From Evaluating Standard Pharmacokinetic-Pharmacodynamic Models
Author:
Affiliation:
1. MedImmune LLC, Clinical Pharmacology, Drug Metabolism, and Pharmacokinetics; Cambridge UK
Publisher
Wiley
Subject
Pharmacology (medical),Modelling and Simulation
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1038/psp.2013.77/fullpdf
Reference8 articles.
1. Systems pharmacology models can be used to understand complex pharmacokinetic-pharmacodynamic behavior: an example using 5-lipoxygenase inhibitors;Demin;CPT Pharmacometrics Syst. Pharmacol.,2013
2. Negative modeling results: a dime a dozen or a stepping stone to scientific discovery?;Hendriks;CPT Pharmacometrics Syst. Pharmacol.,2013
3. Insulin signaling in type 2 diabetes: experimental and modeling analyses reveal mechanisms of insulin resistance in human adipocytes;Brännmark;J. Biol. Chem.,2013
4. Mechanism-based population modelling of the effects of vildagliptin on GLP-1, glucose and insulin in patients with type 2 diabetes;Landersdorfer;Br. J. Clin. Pharmacol.,2012
5. Predicting nonlinear changes in bone mineral density over time using a multiscale systems pharmacology model;Peterson;CPT Pharmacometrics Syst. Pharmacol.,2012
Cited by 29 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. An industry perspective on current QSP trends in drug development;Journal of Pharmacokinetics and Pharmacodynamics;2024-03-05
2. Towards a comprehensive assessment of QSP models: what would it take?;Journal of Pharmacokinetics and Pharmacodynamics;2022-08-13
3. Evaluation framework for systems models;CPT: Pharmacometrics & Systems Pharmacology;2022-01-10
4. Virtual Populations for Quantitative Systems Pharmacology Models;Methods in Molecular Biology;2022
5. Physiologically‐Based Pharmacokinetic Modeling to Support Determination of Bioequivalence for Dermatological Drug Products: Scientific and Regulatory Considerations;Clinical Pharmacology & Therapeutics;2021-07-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3