Quantitative Systems Pharmacology Model of NO Metabolome and Methemoglobin Following Long-Term Infusion of Sodium Nitrite in Humans-Reference-Cited by-同舟云学术

Quantitative Systems Pharmacology Model of NO Metabolome and Methemoglobin Following Long-Term Infusion of Sodium Nitrite in Humans

Published:2013-07 Issue:7 Volume:2 Page:60
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT: Pharmacometrics & Systems Pharmacology

Author:

Vega-Villa K¹,Pluta R²,Lonser R²³,Woo S¹

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy; The University of Oklahoma Health Sciences Center; Oklahoma USA

2. Neurosurgical Biology and Therapeutics Section, Division of Intramural Research; National Institute of Neurological Disorders and Stroke, National Institutes of Health; Maryland USA

3. Department of Neurological Surgery; The Ohio State University Wexner Medical Center; Ohio USA

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1038/psp.2013.35/fullpdf

Reference46 articles.

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2. Erythrocytes are the major intravascular storage sites of nitrite in human blood;Dejam;Blood,2005

3. Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation;Gladwin;Am. J. Physiol. Heart Circ. Physiol.,2006

4. Nitric oxide stimulates myoglobin gene and protein expression in vascular smooth muscle;Rayner;Biochem. J.,2009

5. Metabolic fate of an oral dose of 15N-labeled nitrate in humans: effect of diet supplementation with ascorbic acid;Wagner;Cancer Res.,1983

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