High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/ng0601_147.pdf
Reference25 articles.
1. Fliss, M.S. et al. Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287, 2017–2019 (2000).
2. Polyak, K. et al. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nature Genet. 20, 291–293 (1998).
3. Alonso, A. et al. Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis. Electrophoresis 18, 682–685 (1997).
4. Richard, S.M. et al. Nuclear and mitochondrial genome instability in human breast cancer. Cancer Res. 60, 4231–4237 (2000).
5. Habano, W., Nakamura, S. & Sugai, T. Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: Evidence for mismatch repair systems in mitochondrial genome. Oncogene 17, 1931–1937 (1998).
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