Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis-Reference-Cited by-同舟云学术

Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis

Published:2017-10-09 Issue:11 Volume:23 Page:1298-1308
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Xie Cen,Yagai Tomoki,Luo Yuhong,Liang Xianyi,Chen Tao,Wang Qiong,Sun Dongxue,Zhao Jie,Ramakrishnan Sadeesh K,Sun Lulu,Jiang Chunmei,Xue Xiang^ORCID,Tian Yuan,Krausz Kristopher W,Patterson Andrew D^ORCID,Shah Yatrik M,Wu Yue,Jiang Changtao,Gonzalez Frank J^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.4412.pdf

Reference60 articles.

1. Ray, K. NAFLD-the next global epidemic. Nat. Rev. Gastroenterol. Hepatol. 10, 621 (2013).

2. Chalasani, N. et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 142, 1592–1609 (2012).

3. Rotman, Y. & Sanyal, A.J. Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease. Gut 66, 180–190 (2017).

4. Ju, C., Colgan, S.P. & Eltzschig, H.K. Hypoxia-inducible factors as molecular targets for liver diseases. J. Mol. Med. (Berl.) 94, 613–627 (2016).

5. Semenza, G.L. & Wang, G.L. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell. Biol. 12, 5447–5454 (1992).

Cited by 121 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ameliorating effects of the HIF-2α inhibitor PT2385 on high-altitude polycythemia;European Journal of Pharmaceutical Sciences;2024-10

2. HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis;Science Translational Medicine;2024-09-11

3. Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism;Acta Pharmaceutica Sinica B;2024-09

4. A microbial metabolite inhibits the HIF-2α-ceramide pathway to mediate the beneficial effects of time-restricted feeding on MASH;Cell Metabolism;2024-08

5. Ceramides are fuel gauges on the drive to cardiometabolic disease;Physiological Reviews;2024-07-01