The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases-Reference-Cited by-同舟云学术

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

Published:2011-04 Issue:5 Volume:12 Page:463-469
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Rep

Author:

Chowdhury Rasheduzzaman¹,Yeoh Kar Kheng¹,Tian Ya‐Min²,Hillringhaus Lars¹,Bagg Eleanor A¹,Rose Nathan R¹,Leung Ivanhoe K H¹,Li Xuan S³,Woon Esther C Y¹,Yang Ming¹,McDonough Michael A¹,King Oliver N¹,Clifton Ian J¹,Klose Robert J³,Claridge Timothy D W¹,Ratcliffe Peter J²,Schofield Christopher J¹,Kawamura Akane¹

Affiliation:

1. Chemistry Research Laboratory, Department of Chemistry, University of Oxford Mansfield Road Oxford OX1 3TA UK

2. Henry Wellcome Building for Molecular Physiology, Department of Clinical Medicine, University of Oxford Roosevelt Drive Oxford OX3 7BN UK

3. Epigenetic Regulation of Chromatin Function Group, Department of Biochemistry, University of Oxford South Parks Road Oxford OX1 3QU UK

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1038/embor.2011.43

Reference31 articles.

1. Structural Insights into Histone Demethylation by JMJD2 Family Members

2. Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases

3. Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor

4. Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

5. Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

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