Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile-Reference-Cited by-同舟云学术

Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile

Published:2020-10-13 Issue:2 Volume:34 Page:264-279
ISSN:0893-3952
Container-title:Modern Pathology
language:en
Short-container-title:Mod Pathol

Author:

Giannikou Krinio,Zhu Zachary,Kim Jaegil,Winden Kellen D.,Tyburczy Magdalena E.,Marron David,Parker Joel S.^ORCID,Hebert Zachary^ORCID,Bongaarts Anika,Taing Len,Long Henry W.,Pisano William V.,Alexandrescu Sanda,Godlewski Brianna,Nellist Mark,Kotulska Katarzyna,Jozwiak Sergiusz^ORCID,Roszkowski Marcin,Mandera Marek^ORCID,Thiele Elizabeth A.,Lidov Hart,Getz Gad,Devinsky Orrin,Lawrence Michael S.,Ligon Keith L.,Ellison David W.,Sahin Mustafa^ORCID,Aronica Eleonora,Meredith David M.^ORCID,Kwiatkowski David J.

Funder

The Engles Family for Research in TSC and LAM

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Link

https://www.nature.com/articles/s41379-020-00659-9.pdf

Reference50 articles.

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2. Kotulska K, Borkowska J, Roszkowski M, Mandera M, Daszkiewicz P, Drabik K, et al. Surgical treatment of subependymal giant cell astrocytoma in tuberous sclerosis complex patients. Pediatr Neurol. 2014;50:307–12.

3. Henske EP, Jóźwiak S, Kingswood JC, Sampson JR, Thiele EA. Tuberous sclerosis complex. Nat Rev Dis Prim. 2016;2:16035.