Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent TSC1/TSC2 biallelic inactivation, and no BRAF mutations

Author:

Bongaarts Anika1,Giannikou Krinio2,Reinten Roy J.1,Anink Jasper J.1,Mills James D.1,Jansen Floor E.3,Spliet Wim G.M.4,den Dunnen Willfred F.A.5,Coras Roland6,Blümcke Ingmar6,Paulus Werner7,Scholl Theresa8,Feucht Martha8,Kotulska Katarzyna9,Jozwiak Sergiusz10,Buccoliero Anna Maria11,Caporalini Chiara11,Giordano Flavio12,Genitori Lorenzo12,Söylemezoğlu Figen13,Pimentel José14,Nellist Mark15,Schouten-van Meeteren Antoinette Y.N.16,Nag Anwesha17,Mühlebner Angelika18,Kwiatkowski David J.2,Aronica Eleonora11819

Affiliation:

1. Department of (Neuro)Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

2. Division of Pulmonary and Critical Care Medicine and of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

3. Department of Pediatric Neurology, University Medical Center Utrecht, Utrecht, The Netherlands

4. Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands

5. Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

6. Department of Neuropathology, University Hospital Erlangen, Erlangen, Germany

7. Institute of Neuropathology, University Hospital Münster, Münster, Germany

8. Department of Pediatrics, Medical University of Vienna, Vienna, Austria

9. Department of Neurology and Epileptology, Children's Memorial Health Institute, Warsaw, Poland

10. Department of Child Neurology, Medical University of Warsaw, Warsaw, Poland

11. Pathology Unit, Anna Meyer Children's Hospital, Florence, Italy

12. Department of Neurosurgery, Anna Meyer Children's Hospital, Florence, Italy

13. Department of Pathology, Faculty of Medicine, Hacettepe University, Ankara, Turkey

14. Department of Neurology, Hospital de Santa Maria, Lisbon, Portugal

15. Department of Clinical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands

16. Department of Pediatric Oncology, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

17. Center for Cancer Genome Discovery, Dana Farber Cancer Institute, Boston, Massachusetts, USA

18. Stichting Epilepsie Instellingen Nederland (SEIN), The Netherlands

19. Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands

Publisher

Impact Journals, LLC

Subject

Oncology

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