Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair-Reference-Cited by-同舟云学术

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Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair

Published:2012-01 Issue:1 Volume:3 Page:e252-e252
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Bulgar A D,Weeks L D,Miao Y,Yang S,Xu Y,Guo C,Markowitz S,Oleinick N,Gerson S L,Liu L

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis2011135.pdf

Reference42 articles.

1. Hanauske AR, Chen V, Paoletti P, Niyikiza C . Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors. Oncologist 2001; 6: 363–373.

2. Goldman DL, Zhao R . Molecular, biochemical and cellular pharmacology of pemetrexed. Semin Oncol 2002; 29: S3–S17.

3. Houghton JA, Weiss KD, Williams LG, Torrance PM, Houghton PJ . Relationship between 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration in xenografts of human colon adenocarcinomas. Biochem Pharmacol 1986; 35: 1351–1358.

4. Krokan HE, Standal R, Slupphaug G . DNA glycosylases in base excision repair of DNA. Biochem J 1997; 325: 1–16.

5. Yoon JH, Iwai S, O’Connor TR, Pfeifer GP . Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. Nucleic Acids Res 2003; 31: 5399–5404.

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3. Impact of DNA ligase inhibition on the nick sealing of polβ nucleotide insertion products at the downstream steps of base excision repair pathway;Mutagenesis;2024-05-13

4. Detection of Uracil-Excising DNA Glycosylases in Cancer Cell Samples Using a Three-Dimensional DNAzyme Walker;ACS Measurement Science Au;2024-05-08

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