Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology
Link
http://www.nature.com/articles/cddis2015298.pdf
Reference35 articles.
1. D’Orazi G, Cecchinelli B, Bruno T, Manni I, Higashimoto Y, Saito S et al. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol 2002; 4: 11–19.
2. Kim EA, Kim JE, Sung KS, Choi DW, Lee BJ, Choi CY . Homeodomain-interacting protein kinase 2 (HIPK2) targets beta-catenin for phosphorylation and proteasomal degradation. Biochem Biophys Res Commun 2010; 394: 966–971.
3. Hattangadi SM, Burke KA, Lodish HF . Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation. Blood 2010; 115: 4853–4861.
4. Isono K, Nemoto K, Li Y, Takada Y, Suzuki R, Katsuki M et al. Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol 2006; 26: 2758–2771.
5. Rinaldo C, Moncada A, Gradi A, Ciuffini L, D'Eliseo D, Siepi F et al. HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody. Mol Cell 2012; 47: 87–98.
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Phenotypical, genotypical and pathological characterization of the moonwalker mouse, a model of ataxia;Neurobiology of Disease;2024-06
2. Metabolic rewiring and autophagy inhibition correct lysosomal storage disease in mucopolysaccharidosis IIIB;iScience;2024-03
3. miR135a administration ameliorates brain ischemic damage by preventing TRPM7 activation during brain ischemia;CNS Neuroscience & Therapeutics;2023-09-18
4. HIPK2 in the physiology of nervous system and its implications in neurological disorders;Biochimica et Biophysica Acta (BBA) - Molecular Cell Research;2023-06
5. HIPK2 in cancer biology and therapy: Recent findings and future perspectives;Cellular Signalling;2023-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3