Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation-Reference-Cited by-同舟云学术

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Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation

Published:2015-02 Issue:2 Volume:6 Page:e1657-e1657
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Rettig I,Koeneke E,Trippel F,Mueller W C,Burhenne J,Kopp-Schneider A,Fabian J,Schober A,Fernekorn U,von Deimling A,Deubzer H E,Milde T,Witt O,Oehme I

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis201524.pdf

Reference48 articles.

1. Brodeur GM . Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 2003; 3: 203–216.

2. Van Roy N, De Preter K, Hoebeeck J, Van Maerken T, Pattyn F, Mestdagh P et al. The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy. Genome Med 2009; 1: 74.

3. Witt O, Deubzer HE, Lodrini M, Milde T, Oehme I . Targeting histone deacetylases in neuroblastoma. Curr Pharm Des 2009; 15: 436–447.

4. Buggy JJ, Sideris ML, Mak P, Lorimer DD, McIntosh B, Clark JM . Cloning and characterization of a novel human histone deacetylase, HDAC8. Biochem J 2000; 350 (Part 1): 199–205.

5. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 2009; 325: 834–840.

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