Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology
Link
http://www.nature.com/articles/cddis2016404.pdf
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3. Yuneva MO, Fan TW, Allen TD, Higashi RM, Ferraris DV, Tsukamoto T et al. The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. Cell Metab 2012; 15: 157–170.
4. van den Heuvel APJ, Jing J, Wooster RF, Bachman KE . Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth. Cancer Biol Ther 2012; 13: 1185–1194.
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