KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a-Reference-Cited by-同舟云学术

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KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a

Published:2013-08 Issue:8 Volume:4 Page:e745-e745
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Huang L,Wang H-Y,Li J-D,Wang J-H,Zhou Y,Luo R-Z,Yun J-P,Zhang Y,Jia W-H,Zheng M

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis2013256.pdf

Reference39 articles.

1. Stewart M . Molecular mechanism of the nuclear protein import cycle. Nat Rev Mol Cell Biol 2007; 8: 195–208.

2. Kelley JB, Talley AM, Spencer A, Gioeli D, Paschal BM . Karyopherin alpha 7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors. BMC Cell Biol 2010; 11: 63.

3. Radu A, Blobel G, Moore MS . Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Proc Natl Acad Sci USA 1995; 92: 1769–1773.

4. Weis K, Mattaj IW, Lamond AI . Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences. Science 1995; 268: 1049–1053.

5. Gorlich D, Henklein P, Laskey RA, Hartmann EA . 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus. EMBO J 1996; 15: 1810–1817.

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