Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.nature.com/articles/s41574-022-00671-w.pdf
Reference204 articles.
1. Volkov, P. et al. Whole-genome bisulfite sequencing of human pancreatic islets reveals novel differentially methylated regions in type 2 diabetes pathogenesis. Diabetes 66, 1074–1085 (2017).
2. Jones, P. A. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet. 13, 484–492 (2012).
3. Eliasson, L. & Regazzi, R. Micro(RNA) management and mismanagement of the islet. J. Mol. Biol. 432, 1419–1428 (2020).
4. Mahajan, A. et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat. Genet. 50, 1505–1513 (2018).
5. Locke, A. E. et al. Genetic studies of body mass index yield new insights for obesity biology. Nature 518, 197–206 (2015).
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