N501Y mutation imparts cross-species transmission of SARS-CoV-2 to mice by enhancing receptor binding
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics
Link
http://www.nature.com/articles/s41392-021-00704-2.pdf
Reference5 articles.
1. Shi, Y. et al. COVID-19 infection: the perspectives on immune responses. Cell Death Differ. 27, 1451–1454 (2020).
2. Korber, B. et al. Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell 182, 812–827. e19 (2020).
3. Jiang, X. et al. Bimodular effects of D614G mutation on the spike glycoprotein of SARS-CoV-2 enhance protein processing, membrane fusion, and viral infectivity. Signal Transduct. Target Ther. 5, 268–271 (2020).
4. Gu, H. et al. Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy. Science 369, 1603–1607 (2020).
5. Li, Q. et al. SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape. Cell 184, 2362–2371 (2021).
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