TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling-Reference-Cited by-同舟云学术

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling

Published:2017-05 Issue:7654 Volume:545 Page:365-369
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Wang Bin,Jie Zuliang,Joo Donghyun,Ordureau Alban,Liu Pengda,Gan Wenjian,Guo Jianping,Zhang Jinfang,North Brian J.,Dai Xiangpeng,Cheng Xuhong,Bian Xiuwu,Zhang Lingqiang,Harper J. Wade,Sun Shao-Cong,Wei Wenyi

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature22344.pdf

Reference45 articles.

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2. Aylett, C. H. et al. Architecture of human mTOR complex 1. Science 351, 48–52 (2016)

3. Sancak, Y. et al. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320, 1496–1501 (2008)

4. Zoncu, R. et al. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H+-ATPase. Science 334, 678–683 (2011)

5. Bar-Peled, L., Schweitzer, L. D., Zoncu, R. & Sabatini, D. M. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1. Cell 150, 1196–1208 (2012)

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