Predictive compound accumulation rules yield a broad-spectrum antibiotic-Reference-Cited by-同舟云学术

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Predictive compound accumulation rules yield a broad-spectrum antibiotic

Published:2017-05-10 Issue:7654 Volume:545 Page:299-304
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Richter Michelle F.,Drown Bryon S.,Riley Andrew P.,Garcia Alfredo,Shirai Tomohiro,Svec Riley L.,Hergenrother Paul J.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/nature22308.pdf

Reference64 articles.

1. Payne, D. J., Gwynn, M. N., Holmes, D. J. & Pompliano, D. L. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat. Rev. Drug Discov. 6, 29–40 (2007)

2. Fischbach, M. A. & Walsh, C. T. Antibiotics for emerging pathogens. Science 325, 1089–1093 (2009)

3. Boucher, H. W. et al. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin. Infect. Dis. 48, 1–12 (2009)

4. Lewis, K. Platforms for antibiotic discovery. Nat. Rev. Drug Discov. 12, 371–387 (2013)

5. Nikaido, H. Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science 264, 382–388 (1994)

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