Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector-Reference-Cited by-同舟云学术

Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector

Published:2016-02 Issue:2 Volume:24 Page:287-297
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Grieger Joshua C,Soltys Stephen M,Samulski Richard Jude

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference36 articles.

1. Critical assessment of current adeno-associated viral vector production and quantification methods;Aucoin;Biotechnol Adv,2008

2. Clinical gene therapy using recombinant adeno-associated virus vectors;Mueller;Gene Ther,2008

3. Adenovirus-associated defective virus particles;Atchison;Science,1965

4. Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication;Buller;J Virol,1981

5. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus;Xiao;J Virol,1998

Cited by 227 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Single-use chromatographic clarification to eliminate endonuclease treatment in production of recombinant adeno-associated viral vectors;Separation and Purification Technology;2025-02

2. Unlocking DOE potential by selecting the most appropriate design for rAAV optimization;Molecular Therapy - Methods & Clinical Development;2024-12

3. A Novel Method for Separating Full and Empty Adeno-Associated Viral Capsids Using Ultrafiltration;Membranes;2024-09-12

4. Factors affecting rAAV titers during triple-plasmid transient transfection in HEK-293 cells;Biotechnology Letters;2024-09-11

5. Enhanced ER protein processing gene expression increases rAAV yield and full capsid ratio in HEK293 cells;Applied Microbiology and Biotechnology;2024-09-04