A small molecule, orally active, α 4 β 1 /α 4 β 7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats-Reference-Cited by-同舟云学术

A small molecule, orally active, α 4 β 1 /α 4 β 7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats

Published:2006-03 Issue:6 Volume:147 Page:661-670
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:

Author:

Cortijo Julio,Sanz María-Jesús,Iranzo Arantxa,Montesinos José Luis,Nabah Yafa Naim Abu,Alfón José,Gómez Luis A,Merlos Manuel,Morcillo Esteban J

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1038/sj.bjp.0706658/fullpdf

Reference60 articles.

1. Blockade of late-phase airway responses and airway hyperresponsiveness in allergic sheep with a small-molecule peptide inhibitor of VLA-4;ABRAHAM;Am. J. Respir. Crit. Care Med.,1997

2. A small-molecule, tight-binding inhibitor of the integrin alpha(4)beta(1) blocks antigen-induced airway responses and inflammation in experimental asthma in sheep;ABRAHAM;Am. J. Respir. Crit. Care Med.,2000

3. Alpha 4-integrins mediate antigen-induced late bronchial responses and prolonged airway hyperresponsiveness in sheep;ABRAHAM;J. Clin. Invest.,1994

4. Expression of endothelial and leukocyte adhesion molecules interacellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma;BENTLEY;J. Allergy Clin. Immunol.,1993

5. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1;BERLIN;Cell,1993

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The integrin receptor beta7 subunit mediates airway remodeling and hyperresponsiveness in allergen exposed mice;Respiratory Research;2024-07-12

2. Microneedle-Mediated Immunization Promotes Lung CD8+ T-Cell Immunity;Journal of Investigative Dermatology;2023-10

3. METTL3 mediates chemoresistance by enhancing AML homing and engraftment via ITGA4;Leukemia;2022-10-20

4. Emerging therapies targeting eosinophil-mediated inflammation in chronic allergic conjunctivitis;The Ocular Surface;2022-10

5. Mucosal integrin α4β7 blockade fails to reduce the seeding and size of viral reservoirs in SIV‐infected rhesus macaques;The FASEB Journal;2021-01-23