Blockade of Late-phase Airway Responses and Airway Hyperresponsiveness in Allergic Sheep with a Small-molecule Peptide Inhibitor of VLA-4-Reference-Cited by-同舟云学术

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Blockade of Late-phase Airway Responses and Airway Hyperresponsiveness in Allergic Sheep with a Small-molecule Peptide Inhibitor of VLA-4

Published:1997-09 Issue:3 Volume:156 Page:696-703
ISSN:1073-449X
Container-title:American Journal of Respiratory and Critical Care Medicine
language:en
Short-container-title:Am J Respir Crit Care Med

Author:

ABRAHAM WILLIAM M.,AHMED ASHFAQ,SIELCZAK MAREK W.,NARITA MASAHIRO,ARRHENIUS THOMAS,ELICES MARIANO J.

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Reference27 articles.

1. Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity

2. Airway Hyperresponsiveness, Increased Intracellular Spaces of Bronchial Epithelium, and Increased Infiltration of Eosinophils and Lymphocytes in Bronchial Mucosa in Asthma

3. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

4. Mechanisms of eosinophil adherence to cultured vascular endothelial cells. Eosinophils bind to the cytokine-induced ligand vascular cell adhesion molecule-1 via the very late activation antigen-4 integrin receptor.

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1. Process optimization of chiral extraction of 2,3-diphenylpropionic acid by experiment and simulation;Process Biochemistry;2019-01

2. Heterocycle-substituted proline dipeptides as potent VLA-4 antagonists;Bioorganic & Medicinal Chemistry Letters;2010-02

3. Modeling of asthma, COPD and cystic fibrosis in sheep;Pulmonary Pharmacology & Therapeutics;2008-10

4. Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma;Journal of Leukocyte Biology;2007-09-28

5. A small molecule, orally active, α 4 β 1 /α 4 β 7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats;British Journal of Pharmacology;2006-03

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