Drugs and trafficking of ion channels: a new pro-arrhythmic threat on the horizon?

Author:

van der Heyden M A G,Smits M E,Vos M A

Publisher

Wiley

Subject

Pharmacology

Reference29 articles.

1. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism;Anderson;Circulation,2006

2. Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide;Carmeliet;J Pharmacol Exp Ther,1992

3. Pentamidine reduces hERG expression to prolong the QT interval;Cordes;Br J Pharmacol,2005

4. Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current;Drolet;J Pharmacol Exp Ther,1999

5. Unusual effects of a QT prolonging drug, arsenic trioxide, on cardiac potassium currents;Drolet;Circulation,2004

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