Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+channels enhancing the antimyotonic activityin vivo-Reference-Cited by-同舟云学术

Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+channels enhancing the antimyotonic activityin vivo

Published:2001-12 Issue:7 Volume:134 Page:1523-1531
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:

Author:

Talon Sophie,De Luca Annamaria,De Bellis Michela,Desaphy Jean-François,Lentini Giovanni,Scilimati Antonio,Corbo Filomena,Franchini Carlo,Tortorella Paolo,Jockusch Harald,Conte Camerino Diana

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1038/sj.bjp.0704366/fullpdf

Reference33 articles.

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3. From mutation to myotonia in sodium channel disorders;CANNON;Neuromuscul. Disord.,1997

4. Common modes of drug action on Na+ channels: local anesthesics, antiarrhythmics and anticonvulsants;CATTERALL;Trends Pharmacol. Sci.,1987

5. Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats;CONTE CAMERINO;Neuromuscul. Disord.,2000

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