Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine
Author:
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1038/sj.bjp.0704784/fullpdf
Reference66 articles.
1. KvLQT1 and IsK (minK) proteins associate to form the IKs cardiac potassium current;BARHANIN;Nature,1996
2. Therapeutic drug monitoring of flecainide in serum using high-performance liquid chromatography and electrospray mass spectrometry;BREINDAHL;J. Chromatogr. B. Biomed. Sci. Appl.,2000
3. Kinetics of onset of rate-dependent effects of class l antiarrhythmic drugs are important in determining their effects on refractoriness in guinea-pig ventricle, and provide a theoretical basis for their subclassification;CAMPBELL;Cardiovasc. Res.,1983
4. Differential effects on action potential duration of class IA, B, and C antiarrhythmic drugs: modulation by stimulation rate and extracellular K+ concentration;CAMPBELL;Clin. Exp. Pharmacol. Physiol.,1991
5. K+ channels and control of ventricular repolarisation in the heart;CARMELIET;Fundam. Clin. Pharmacol.,1993
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