Spatial heterogeneity in medulloblastoma
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Published:2017-04-10
Issue:5
Volume:49
Page:780-788
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Morrissy A Sorana, Cavalli Florence M G, Remke MarcORCID, Ramaswamy VijayORCID, Shih David J H, Holgado Borja L, Farooq Hamza, Donovan Laura K, Garzia Livia, Agnihotri Sameer, Kiehna Erin N, Mercier Eloi, Mayoh Chelsea, Papillon-Cavanagh SimonORCID, Nikbakht Hamid, Gayden Tenzin, Torchia Jonathon, Picard Daniel, Merino Diana MORCID, Vladoiu Maria, Luu Betty, Wu Xiaochong, Daniels Craig, Horswell Stuart, Thompson Yuan Yao, Hovestadt Volker, Northcott Paul A, Jones David T W, Peacock John, Wang XinORCID, Mack Stephen C, Reimand Jüri, Albrecht Steffen, Fontebasso Adam M, Thiessen Nina, Li Yisu, Schein Jacqueline E, Lee Darlene, Carlsen Rebecca, Mayo Michael, Tse Kane, Tam Angela, Dhalla Noreen, Ally Adrian, Chuah Eric, Cheng Young, Plettner Patrick, Li Haiyan I, Corbett Richard D, Wong Tina, Long William, Loukides James, Buczkowicz Pawel, Hawkins Cynthia E, Tabori Uri, Rood Brian R, Myseros John S, Packer Roger J, Korshunov Andrey, Lichter Peter, Kool Marcel, Pfister Stefan M, Schüller Ulrich, Dirks Peter, Huang Annie, Bouffet Eric, Rutka James T, Bader Gary DORCID, Swanton Charles, Ma Yusanne, Moore Richard A, Mungall Andrew JORCID, Majewski Jacek, Jones Steven J M, Das SunitORCID, Malkin David, Jabado Nada, Marra Marco A, Taylor Michael D
Publisher
Springer Science and Business Media LLC
Reference51 articles.
1. Northcott, P.A. et al. Medulloblastoma comprises four distinct molecular variants. J. Clin. Oncol. 29, 1408–1414 (2011). 2. Kleinman, C.L. et al. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR. Nat. Genet. 46, 39–44 (2014). 3. Versteege, I. et al. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394, 203–206 (1998). 4. Pietsch, T. et al. Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort. Acta Neuropathol. 128, 137–149 (2014). 5. Remke, M., Ramaswamy, V. & Taylor, M.D. Medulloblastoma molecular dissection: the way toward targeted therapy. Curr. Opin. Oncol. 25, 674–681 (2013).
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