A sestrin-dependent Erk–Jnk–p38 MAPK activation complex inhibits immunity during aging
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/ni.3665.pdf
Reference39 articles.
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3. Lutz, W., Sanderson, W. & Scherbov, S. The coming acceleration of global population ageing. Nature 451, 716–719 (2008).
4. Di Mitri, D. et al. Reversible senescence in human CD4+CD45RA+CD27− memory T cells. J. Immunol. 187, 2093–2100 (2011).
5. Lanna, A., Henson, S.M., Escors, D. & Akbar, A.N. The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells. Nat. Immunol. 15, 965–972 (2014).
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