Macrocyclic colibactins
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
https://www.nature.com/articles/s41557-020-00551-8.pdf
Reference15 articles.
1. Arthur, J. C. et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 338, 120–123 (2012).
2. Li, Z.-R. et al. Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage. Nat. Chem. 11, 880–889 (2019).
3. Nougayrède, J.-P. et al. Escherichia coli induces DNA double-strand breaks in eukaryotic cells. Science 313, 848–851 (2006).
4. Bossuet-Greif, N. et al. The colibactin genotoxin generates DNA interstrand crosslinks in infected cells. MBio 9, e02393–02317 (2018).
5. Colis, L. C. et al. The cytotoxicity of (–)-lomaiviticin A arises from induction of double-strand breaks in DNA. Nat. Chem. 6, 504–510 (2014).
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