T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide–MHC complexes

Published:2018-11-19 Issue:12 Volume:36 Page:1191-1196
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Bentzen Amalie K,Such Lina,Jensen Kamilla K,Marquard Andrea M,Jessen Leon E,Miller Natalie J,Church Candice D,Lyngaa Rikke,Koelle David M,Becker Jürgen C,Linnemann Carsten^ORCID,Schumacher Ton N M^ORCID,Marcatili Paolo,Nghiem Paul,Nielsen Morten,Hadrup Sine R^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt.4303.pdf

Reference50 articles.

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3. Cameron, B.J. et al. Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells. Sci. Transl. Med. 5, 197ra103 (2013).

4. Davis, M.M. & Bjorkman, P.J. T-cell antigen receptor genes and T-cell recognition. Nature 334, 395–402 (1988).

5. Mason, D. A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol. Today 19, 395–404 (1998).

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