Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice-Reference-Cited by-同舟云学术

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

Published:2015-03-16 Issue:4 Volume:33 Page:402-407
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Obenaus Matthias^ORCID,Leitão Catarina^ORCID,Leisegang Matthias,Chen Xiaojing,Gavvovidis Ioannis,van der Bruggen Pierre,Uckert Wolfgang,Schendel Dolores J,Blankenstein Thomas

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt.3147.pdf

Reference46 articles.

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3. Li, L.-P. et al. Transgenic mice with a diverse human T cell antigen receptor repertoire. Nat. Med. 16, 1029–1034 (2010).

4. van der Bruggen, P. et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 254, 1643–1647 (1991).

5. Holler, P.D., Chlewicki, L.K. & Kranz, D.M. TCRs with high affinity for foreign pMHC show self-reactivity. Nat. Immunol. 4, 55–62 (2003).

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