Heterologous viral expression systems in fosmid vectors increase the functional analysis potential of metagenomic libraries
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep01107.pdf
Reference51 articles.
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2. Uchiyama, T. & Miyazaki, K. Functional metagenomics for enzyme discovery: challenges to efficient screening. Curr. Opin. Biotechnol 20, 616–622 (2009).
3. Lämmle, K. et al. Identification of novel enzymes with different hydrolytic activities by metagenome expression cloning. J Biotechnol 127, 575–592 (2007).
4. Simon, C., Herath, J., Rockstroh, S. & Daniel, R. Rapid identification of genes encoding DNA polymerases by function-based screening of metagenomic libraries derived from glacial ice. Appl. Environ. Microbiol. 75, 2964–2968 (2009).
5. Sommer, M. O., Dantas, G. & Church, G. M. Functional characterization of the antibiotic resistance reservoir in the human microflora. Science 325, 1128–1131 (2009).
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