A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://www.nature.com/articles/nbt.3781.pdf
Reference39 articles.
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2. Géléoc, G.S. & Holt, J.R. Sound strategies for hearing restoration. Science 344, 1241062 (2014).
3. Zinn, E. et al. In silico reconstruction of the viral evolutionary lineage yields a potent gene therapy vector. Cell Rep. 12, 1056–1068 (2015).
4. Parker, M. & Bitner-Glindzicz, M. Genetic investigations in childhood deafness. Arch. Dis. Child. 100, 271–278 (2015).
5. Stamatiou, G.A. & Stankovic, K.M. A comprehensive network and pathway analysis of human deafness genes. Otol. Neurotol. 34, 961–970 (2013).
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