Improving AZT efficacy
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm0298-132a.pdf
Reference7 articles.
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2. Balzarini, J. et al. The in vitro and in vivo anti-retro-virus activity, and intracellular metabolism of 3′-azido-2′,3′-dideoxythymidine and 2′,3′-dideoxy-cytidine are highly dependent on the cell species. Biochem. Pharmacol. 37, 897–903 (1988).
3. Balzarini, J., Herdewijn, P. & De Clercq, E. Differential patterns of intracellular metabolism of 2′,3′-didehydro-2′,3′-dideoxythymidine and 3′-azido-2′,3′-dideoxythymidine, two potent anti-human immunodeficiency virus compounds. J. Biol. Chem. 264, 6127–6133 (1989).
4. Frick, L.W. et al. Effects of 3′-azido-3′-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells. Biochem. Biophys. Res. Comm. 154, 124–129 (1988).
5. Guettari, N., Loubiere, L., Brisson, E. & Klatzmann, D. Use of Herpes-simplex Virus Thymidine Kinase to Imporve the Antiviral Activity of Zidovudine. Virology 235, 398–405 (1997).
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