Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation-Reference-Cited by-同舟云学术

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Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation

Published:1999-12 Issue:50 Volume:274 Page:35289-35292
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Brundiers Ralf,Lavie Arnon,Veit Thomas,Reinstein Jochen,Schlichting Ilme,Ostermann Nils,Goody Roger S.,Konrad Manfred

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference16 articles.

1. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

2. Differential Patterns of Intracellular Metabolism of 2′,3′-Didehydro-2′,3′-dideoxythymidine and 3′-Azido-2′,3′-dideoxythymidine, Two Potent Anti-human Immunodeficiency Virus Compounds

3. The P-loop — a common motif in ATP- and GTP-binding proteins

4. The bottleneck in AZT activation

5. Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation

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