Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2008291.pdf
Reference59 articles.
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2. Chipuk JE, Cornelius SC, Pultz NJ, Jorgensen JS, Bonham MJ, Kim SJ et al. (2002a). The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3. J Biol Chem 277: 1240–1248.
3. Chipuk JE, Stewart LV, Ranieri A, Song K, Danielpour D . (2002b). Identification and characterization of a novel rat ov-serpin family member, trespin. J Biol Chem 277: 26412–26421.
4. Dabiri G, Tumbarello DA, Turner CE, Van De Water L . (2008). Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop. J Invest Dermatol (in press).
5. Danielpour D . (2005). Functions and regulation of transforming growth factor-beta (TGF-beta) in the prostate. Eur J Cancer 41: 846–857.
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