Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation-Reference-Cited by-同舟云学术

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Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation

Published:2016-02-24 Issue:6 Volume:9 Page:1418-1428
ISSN:1933-0219
Container-title:Mucosal Immunology
language:en
Short-container-title:Mucosal Immunol

Author:

Banerjee S,Sindberg G,Wang F,Meng J,Sharma U,Zhang L,Dauer P,Chen C,Dalluge J,Johnson T,Roy S

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/mi20169.pdf

Reference51 articles.

1. Ninković, J. & Roy, S. Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms. Am. J. Pathol. 180, 1068–1079 (2012).

2. Roy, S. et al. Opioid drug abuse and modulation of immune function: consequences in the susceptibility to opportunistic infections. J. Neuroimmune. Pharmacol. 6, 442–465 (2011).

3. Meng, J. et al. Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner. PLoS One 8, e54040 (2013).

4. Banerjee, S. et al. Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a. Sci. Rep. 3, 1977 (2013).

5. Hilburger, M.E. et al. Morphine induces sepsis in mice. J. Infect. Dis. 176, 183–188 (1997).

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