Pass-back chain extension expands multimodular assembly line biosynthesis
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/s41589-019-0385-4.pdf
Reference57 articles.
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2. Cane, D. E. Programming of erythromycin biosynthesis by a modular polyketide synthase. J. Biol. Chem. 285, 27517–27523 (2010).
3. Robbel, L. & Marahiel, M. A. Daptomycin, a bacterial lipopeptide synthesized by a nonribosomal machinery. J. Biol. Chem. 285, 27501–27508 (2010).
4. Helfrich, E. J. & Piel, J. Biosynthesis of polyketides by trans-AT polyketide synthases. Nat. Prod. Rep. 33, 231–316 (2016).
5. Sussmuth, R. D. & Mainz, A. Nonribosomal peptide synthesis—principles and prospects. Angew. Chem. Int. Ed. Engl. 56, 3770–3821 (2017).
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