Development of a chemical probe against NUDT15-Reference-Cited by-同舟云学术

Development of a chemical probe against NUDT15

Published:2020-07-20 Issue:10 Volume:16 Page:1120-1128
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Zhang Si Min^ORCID,Desroses Matthieu^ORCID,Hagenkort Anna,Valerie Nicholas C. K.,Rehling Daniel^ORCID,Carter Megan,Wallner Olov,Koolmeister Tobias,Throup Adam,Jemth Ann-Sofie,Almlöf Ingrid,Loseva Olga,Lundbäck Thomas^ORCID,Axelsson Hanna^ORCID,Regmi Shruti,Sarno Antonio,Krämer Andreas,Pudelko Linda,Bräutigam Lars,Rasti Azita,Göttmann Mona,Wiita Elisée,Kutzner Juliane,Schaller Torsten^ORCID,Kalderén Christina,Cázares-Körner Armando,Page Brent D. G.,Krimpenfort Rosa,Eshtad Saeed^ORCID,Altun Mikael^ORCID,Rudd Sean G.^ORCID,Knapp Stefan^ORCID,Scobie Martin,Homan Evert J.,Berglund Ulrika Warpman^ORCID,Stenmark Pål^ORCID,Helleday Thomas

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/s41589-020-0592-z.pdf

Reference54 articles.

1. Nagy, G. N., Leveles, I. & Vertessy, B. G. Preventive DNA repair by sanitizing the cellular (deoxy)nucleoside triphosphate pool. FEBS J. 281, 4207–4223 (2014).

2. Rudd, S. G., Valerie, N. C. K. & Helleday, T. Pathways controlling dNTP pools to maintain genome stability. DNA Repair (Amst.) 44, 193–204 (2016).

3. Bessman, M. J., Frick, D. N. & O’Handley, S. F. The MutT proteins or ‘Nudix’ hydrolases, a family of versatile, widely distributed, ‘housecleaning’ enzymes. J. Biol. Chem. 271, 25059–25062 (1996).

4. Carreras-Puigvert, J. et al. A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family. Nat. Commun. 8, 1541 (2017).

5. Cai, J. P., Ishibashi, T., Takagi, Y., Hayakawa, H. & Sekiguchi, M. Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides. Biochem. Biophys. Res. Commun. 305, 1073–1077 (2003).

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