Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel-Reference-Cited by-同舟云学术

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Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

Published:2024-02 Issue:2 Volume:27 Page:108907
ISSN:2589-0042
Container-title:iScience
language:en
Short-container-title:iScience

Author:

Zhang Si Min,Paulin Cynthia B.J.,Shu Huazhang,Yagüe-Capilla Miriam,Michel Maurice,Marttila Petra,Ortis Florian,Bwanika Henri Colyn,Dirks Christopher,Venkatram Rajagopal Papagudi,Wiita Elisée,Jemth Ann-Sofie,Almlöf Ingrid,Loseva Olga,Hormann Femke M.,Koolmeister Tobias,Linde Erika,Lee Sun,Llona-Minguez Sabin,Haraldsson Martin,Axelsson Hanna,Strömberg Kia,Homan Evert J.,Scobie Martin,Lundbäck Thomas,Helleday Thomas,Rudd Sean G.^ORCID

Funder

Felix Mindus Foundation's contribution to leukemia research

Barncancerfonden

Stiftelsen Clas Groschinskys Minnesfond

Dr Åke Olsson's Foundation for Haematological Research

Åke Wiberg Stiftelse

Sjöbergstiftelsen

IMI

Cancerfonden

Vetenskapsradet

Stiftelsen Lars Hiertas Minne

Publisher

Elsevier BV

Reference75 articles.

1. SAMHD1 Functions and Human Diseases;Coggins;Viruses,2020

2. Targeting the DNA damage response and repair in cancer through nucleotide metabolism;Helleday;Mol. Oncol.,2022

3. The HD domain defines a new superfamily of metal-dependent phosphohydrolases;Aravind;Trends Biochem. Sci.,1998

4. Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase;Powell;J. Biol. Chem.,2011

5. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase;Goldstone;Nature,2011

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The N-terminal SAM domain of the dNTPase SAMHD1 is not required for inhibition by small molecule TH6342;Nucleosides, Nucleotides & Nucleic Acids;2024-06-03

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